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Virus Sensor RIG-I Represses RNA Interference by Interacting with TRBP through LGP2 in Mammalian Cells

Exogenous double-stranded RNAs (dsRNAs) similar to viral RNAs induce antiviral RNA silencing or RNA interference (RNAi) in plants or invertebrates, whereas interferon (IFN) response is induced through activation of virus sensor proteins including Toll like receptor 3 (TLR3) or retinoic acid-inducibl...

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Detalles Bibliográficos
Autores principales: Takahashi, Tomoko, Nakano, Yuko, Onomoto, Koji, Yoneyama, Mitsutoshi, Ui-Tei, Kumiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6210652/
https://www.ncbi.nlm.nih.gov/pubmed/30347765
http://dx.doi.org/10.3390/genes9100511