Influence of Molecular Design on the Targeting Properties of ABD-Fused Mono- and Bi-Valent Anti-HER3 Affibody Therapeutic Constructs

Overexpression of human epidermal growth factor receptor type 3 (HER3) is associated with tumour cell resistance to HER-targeted therapies. Monoclonal antibodies (mAbs) targeting HER3 are currently being investigated for treatment of various types of cancers. Cumulative evidence suggests that affibo...

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Detalles Bibliográficos
Autores principales: Altai, Mohamed, Leitao, Charles Dahlsson, Rinne, Sara S., Vorobyeva, Anzhelika, Atterby, Christina, Ståhl, Stefan, Tolmachev, Vladimir, Löfblom, John, Orlova, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6210767/
https://www.ncbi.nlm.nih.gov/pubmed/30314301
http://dx.doi.org/10.3390/cells7100164

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6210767/
https://www.ncbi.nlm.nih.gov/pubmed/30314301
http://dx.doi.org/10.3390/cells7100164

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