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Method to identify and minimize artifacts induced by fluorescent impurities in single-molecule localization microscopy

The existence of fluorescent impurities has been a long-standing obstacle in single-molecule imaging, which results in sample misidentification and higher localization uncertainty. Spectroscopic single-molecule localization microscopy can record the full fluorescent spectrum of every stochastic sing...

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Detalles Bibliográficos
Autores principales: Davis, Janel L., Dong, Biqin, Sun, Cheng, Zhang, Hao F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society of Photo-Optical Instrumentation Engineers 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6210800/
https://www.ncbi.nlm.nih.gov/pubmed/30334394
http://dx.doi.org/10.1117/1.JBO.23.10.106501