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Protective Effects of 17β-Estradiol on Benzo(e) pyrene[B(e)P]-induced Toxicity in ARPE-19 cells

PURPOSE: The aim of this study was to examine the effect of 17β-estradiol on Benzo(e)pyrene [B(e)P]-induced toxicity in ARPE-19 cells. METHODS: We pretreated ARPE-19 cells with 20 nM and 40 nM 17β-estradiol for 6 hours, followed by addition of 300 μM B(e)P for additional 24 hours. Cell viability was...

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Detalles Bibliográficos
Autores principales: Sapkal, Ashish U., Nashine, Sonali, Mansoor, Saffar, Sharma, Vishal R., Ramirez, Claudio A., Migon, Rafael Z., Gupta, Navin K., Chwa, Marilyn, Kuppermann, Baruch D., Kenney, M. Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6210882/
https://www.ncbi.nlm.nih.gov/pubmed/30479711
http://dx.doi.org/10.4103/jovr.jovr_16_18