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Scavenger receptor BI promotes cytoplasmic accumulation of lipoproteins in clear-cell renal cell carcinoma

Clear-cell renal cell carcinomas (ccRCCs) are characterized by inactivation of the von Hippel-Lindau (VHL) gene and intracellular lipid accumulation by unknown pathomechanisms. The immunochemical analysis of 356 RCCs revealed high abundance of apoA-I and apoB, as well as scavenger receptor BI (SR-BI...

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Detalles Bibliográficos
Autores principales: Velagapudi, Srividya, Schraml, Peter, Yalcinkaya, Mustafa, Bolck, Hella A., Rohrer, Lucia, Moch, Holger, von Eckardstein, Arnold
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6210910/
https://www.ncbi.nlm.nih.gov/pubmed/30173145
http://dx.doi.org/10.1194/jlr.M083311