Prodigiosin-Emerged PI3K/Beclin-1-Independent Pathway Elicits Autophagic Cell Death in Doxorubicin-Sensitive and -Resistant Lung Cancer

Prodigiosin (PG) belongs to a family of prodiginines isolated from gram-negative bacteria. It is a water insoluble red pigment and a potent proapoptotic compound. This study elucidates the anti-tumor activity and underlying mechanism of PG in doxorubicin-sensitive (Dox-S) and doxorubicin-resistant (...

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Detalles Bibliográficos
Autores principales: Chiu, Wei-Jun, Lin, Shian-Ren, Chen, Yu-Hsin, Tsai, May-Jwan, Leong, Max K., Weng, Ching-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6210934/
https://www.ncbi.nlm.nih.gov/pubmed/30282915
http://dx.doi.org/10.3390/jcm7100321

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6210934/
https://www.ncbi.nlm.nih.gov/pubmed/30282915
http://dx.doi.org/10.3390/jcm7100321

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