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Prodigiosin-Emerged PI3K/Beclin-1-Independent Pathway Elicits Autophagic Cell Death in Doxorubicin-Sensitive and -Resistant Lung Cancer
Prodigiosin (PG) belongs to a family of prodiginines isolated from gram-negative bacteria. It is a water insoluble red pigment and a potent proapoptotic compound. This study elucidates the anti-tumor activity and underlying mechanism of PG in doxorubicin-sensitive (Dox-S) and doxorubicin-resistant (...
Autores principales: | Chiu, Wei-Jun, Lin, Shian-Ren, Chen, Yu-Hsin, Tsai, May-Jwan, Leong, Max K., Weng, Ching-Feng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6210934/ https://www.ncbi.nlm.nih.gov/pubmed/30282915 http://dx.doi.org/10.3390/jcm7100321 |
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