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An Analytic Approach Using Candidate Gene Selection and Logic Forest to Identify Gene by Environment Interactions (G × E) for Systemic Lupus Erythematosus in African Americans

Development and progression of many human diseases, such as systemic lupus erythematosus (SLE), are hypothesized to result from interactions between genetic and environmental factors. Current approaches to identify and evaluate interactions are limited, most often focusing on main effects and two-wa...

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Detalles Bibliográficos
Autores principales: Wolf, Bethany J., Ramos, Paula S., Hyer, J. Madison, Ramakrishnan, Viswanathan, Gilkeson, Gary S., Hardiman, Gary, Nietert, Paul J., Kamen, Diane L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6211136/
https://www.ncbi.nlm.nih.gov/pubmed/30326636
http://dx.doi.org/10.3390/genes9100496