iVS analysis to evaluate the impact of scaffold diversity in the binding to cellular targets relevant in cancer

This study reports the application of inverse virtual screening (iVS) methodologies to identify cellular proteins as suitable targets for a library of heterocyclic small-molecules, with potential pharmacological implications. Standard synthetic procedures allow facile generation of these ligands sho...

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Detalles Bibliográficos
Autores principales: Cilibrizzi, Agostino, Floresta, Giuseppe, Abbate, Vincenzo, Giovannoni, Maria Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6211261/
https://www.ncbi.nlm.nih.gov/pubmed/30362379
http://dx.doi.org/10.1080/14756366.2018.1518960

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6211261/
https://www.ncbi.nlm.nih.gov/pubmed/30362379
http://dx.doi.org/10.1080/14756366.2018.1518960

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