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iVS analysis to evaluate the impact of scaffold diversity in the binding to cellular targets relevant in cancer
This study reports the application of inverse virtual screening (iVS) methodologies to identify cellular proteins as suitable targets for a library of heterocyclic small-molecules, with potential pharmacological implications. Standard synthetic procedures allow facile generation of these ligands sho...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6211261/ https://www.ncbi.nlm.nih.gov/pubmed/30362379 http://dx.doi.org/10.1080/14756366.2018.1518960 |