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Computer-aided molecular design of pyrazolotriazines targeting glycogen synthase kinase 3

Numerous studies have highlighted the implications of the glycogen synthase kinase 3 (GSK-3) in several processes associated with Alzheimer’s disease (AD). Therefore, GSK-3 has become a crucial therapeutic target for the treatment of this neurodegenerative disorder. Hereby, we report the design and...

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Detalles Bibliográficos
Autores principales: Sciú, M. Lourdes, Sebastián-Pérez, Victor, Martinez-Gonzalez, Loreto, Benitez, Rocio, Perez, Daniel I., Pérez, Concepción, Campillo, Nuria E., Martinez, Ana, Moyano, E. Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6211276/
https://www.ncbi.nlm.nih.gov/pubmed/30362380
http://dx.doi.org/10.1080/14756366.2018.1530223