FXR and TGR5 Agonists Ameliorate Liver Injury, Steatosis, and Inflammation After Binge or Prolonged Alcohol Feeding in Mice

Bile acids (BAs) activate various dedicated receptors, including the farnesoid X receptor (FXR) and the Takeda G protein‐coupled receptor 5 (TGR5). The FXR agonist obeticholic acid (OCA) is licensed for the treatment of primary biliary cholangitis and has shown promising results in NASH patients, wh...

Descripción completa

Detalles Bibliográficos
Autores principales: Iracheta‐Vellve, Arvin, Calenda, Charles D., Petrasek, Jan, Ambade, Aditya, Kodys, Karen, Adorini, Luciano, Szabo, Gyongyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6211332/
https://www.ncbi.nlm.nih.gov/pubmed/30411084
http://dx.doi.org/10.1002/hep4.1256

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6211332/
https://www.ncbi.nlm.nih.gov/pubmed/30411084
http://dx.doi.org/10.1002/hep4.1256

Ejemplares similares