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FXR and TGR5 Agonists Ameliorate Liver Injury, Steatosis, and Inflammation After Binge or Prolonged Alcohol Feeding in Mice

Bile acids (BAs) activate various dedicated receptors, including the farnesoid X receptor (FXR) and the Takeda G protein‐coupled receptor 5 (TGR5). The FXR agonist obeticholic acid (OCA) is licensed for the treatment of primary biliary cholangitis and has shown promising results in NASH patients, wh...

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Detalles Bibliográficos
Autores principales:	Iracheta‐Vellve, Arvin, Calenda, Charles D., Petrasek, Jan, Ambade, Aditya, Kodys, Karen, Adorini, Luciano, Szabo, Gyongyi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6211332/ https://www.ncbi.nlm.nih.gov/pubmed/30411084 http://dx.doi.org/10.1002/hep4.1256

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