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Multiomics analyses identified epigenetic modulation of the S100A gene family in Kawasaki disease and their significant involvement in neutrophil transendothelial migration

BACKGROUND: Kawasaki disease (KD) is a prevalent pediatric disease worldwide and can cause coronary artery aneurysm as a severe complication. Typically, DNA methylation is thought to repress the expression of nearby genes. However, the cases in which DNA methylation promotes gene expression have bee...

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Detalles Bibliográficos
Autores principales: Huang, Lien-Hung, Kuo, Ho-Chang, Pan, Cheng-Tsung, Lin, Yeong-Shin, Huang, Ying-Hsien, Li, Sung-Chou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6211403/
https://www.ncbi.nlm.nih.gov/pubmed/30382880
http://dx.doi.org/10.1186/s13148-018-0557-1