ALPHLARD: a Bayesian method for analyzing HLA genes from whole genome sequence data

BACKGROUND: Although human leukocyte antigen (HLA) genotyping based on amplicon, whole exome sequence (WES), and RNA sequence data has been achieved in recent years, accurate genotyping from whole genome sequence (WGS) data remains a challenge due to the low depth. Furthermore, there is no method to...

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Detalles Bibliográficos
Autores principales: Hayashi, Shuto, Yamaguchi, Rui, Mizuno, Shinichi, Komura, Mitsuhiro, Miyano, Satoru, Nakagawa, Hidewaki, Imoto, Seiya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6211482/
https://www.ncbi.nlm.nih.gov/pubmed/30384854
http://dx.doi.org/10.1186/s12864-018-5169-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6211482/
https://www.ncbi.nlm.nih.gov/pubmed/30384854
http://dx.doi.org/10.1186/s12864-018-5169-9

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