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ALPHLARD: a Bayesian method for analyzing HLA genes from whole genome sequence data
BACKGROUND: Although human leukocyte antigen (HLA) genotyping based on amplicon, whole exome sequence (WES), and RNA sequence data has been achieved in recent years, accurate genotyping from whole genome sequence (WGS) data remains a challenge due to the low depth. Furthermore, there is no method to...
Autores principales: | Hayashi, Shuto, Yamaguchi, Rui, Mizuno, Shinichi, Komura, Mitsuhiro, Miyano, Satoru, Nakagawa, Hidewaki, Imoto, Seiya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6211482/ https://www.ncbi.nlm.nih.gov/pubmed/30384854 http://dx.doi.org/10.1186/s12864-018-5169-9 |
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