Basal pharmacokinetic parameters of topically applied diacerein in pediatric patients with generalized severe epidermolysis bullosa simplex

ABSTRACT: Generalized severe epidermolysis bullosa simplex (EBS-gen sev) is caused by mutations within either the KRT5 or KRT14 gene, phenotypically resulting in blistering and wounding of the skin and mucous membranes after minor mechanical friction. In a clinical phase 2/3 trial, diacerein has rec...

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Detalles Bibliográficos
Autores principales: Ablinger, Michael, Felder, Thomas K., Wimmer, Monika, Zauner, Roland, Hofbauer, Peter, Lettner, Thomas, Wolkersdorfer, Martin, Lagler, Florian B., Diem, Anja, Bauer, Johann W., Wally, Verena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6211505/
https://www.ncbi.nlm.nih.gov/pubmed/30382914
http://dx.doi.org/10.1186/s13023-018-0940-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6211505/
https://www.ncbi.nlm.nih.gov/pubmed/30382914
http://dx.doi.org/10.1186/s13023-018-0940-1

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