CRISPR/Cas9 Knockout Strategies to Ablate CCAT1 lncRNA Gene in Cancer Cells

BACKGROUND: With the increasing discovery of long noncoding RNAs (lncRNAs), the application of functional techniques that could have very specific, efficient, and robust effects and readouts is necessary. Here, we have applied and analyzed three gene knockout (KO) strategies to ablate the CCAT1 gene...

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Detalles Bibliográficos
Autores principales: Zare, Khadijeh, Shademan, Milad, Ghahramani Seno, Mohammad M., Dehghani, Hesam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6211572/
https://www.ncbi.nlm.nih.gov/pubmed/30410426
http://dx.doi.org/10.1186/s12575-018-0086-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6211572/
https://www.ncbi.nlm.nih.gov/pubmed/30410426
http://dx.doi.org/10.1186/s12575-018-0086-5

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