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Lobaplatin inhibits breast cancer progression, cell proliferation while it induces cell apoptosis by downregulating MTDH expression

OBJECTIVE: Lobaplatin shows antitumor activity against a wide range of tumors, including metastatic breast cancer (BCa). The overexpression of metadherin (MTDH) is associated with poor prognosis of BCa patients. This study was designed to investigate the effect of lobaplatin on MCF-7 cell proliferat...

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Detalles Bibliográficos
Autores principales: Tian, Wuguo, Hao, Shuai, Gao, Bo, Jiang, Yan, Zhang, Xiaohua, Zhang, Shu, Guo, Lingji, Zhao, Jianjie, Zhang, Gang, Chen, Yi, Li, Zhirong, Luo, Donglin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6211578/
https://www.ncbi.nlm.nih.gov/pubmed/30464390
http://dx.doi.org/10.2147/DDDT.S163157