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BRCA1-BARD1 associate with the synaptonemal complex and pro-crossover factors and influence RAD-51 dynamics during Caenorhabditis elegans meiosis

During meiosis, the maternal and paternal homologous chromosomes must align along their entire length and recombine to achieve faithful segregation in the gametes. Meiotic recombination is accomplished through the formation of DNA double-strand breaks, a subset of which can mature into crossovers to...

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Detalles Bibliográficos
Autores principales: Janisiw, Eva, Dello Stritto, Maria Rosaria, Jantsch, Verena, Silva, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6211622/
https://www.ncbi.nlm.nih.gov/pubmed/30383754
http://dx.doi.org/10.1371/journal.pgen.1007653