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Chromatin conformation and transcriptional activity are permissive regulators of DNA replication initiation in Drosophila

Chromatin structure has emerged as a key contributor to spatial and temporal control over the initiation of DNA replication. However, despite genome-wide correlations between early replication of gene-rich, accessible euchromatin and late replication of gene-poor, inaccessible heterochromatin, a cau...

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Detalles Bibliográficos
Autores principales: Armstrong, Robin L., Penke, Taylor J.R., Strahl, Brian D., Matera, A. Gregory, McKay, Daniel J., MacAlpine, David M., Duronio, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6211642/
https://www.ncbi.nlm.nih.gov/pubmed/30279224
http://dx.doi.org/10.1101/gr.239913.118