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Multiple membrane extrusion sites drive megakaryocyte migration into bone marrow blood vessels

Platelets, cells central to hemostasis and thrombosis, are formed from parent cell megakaryocytes. Although the process is highly efficient in vivo, our ability to generate them in vitro is still remarkably inefficient. We proposed that greater understanding of the process in vivo is needed and used...

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Detalles Bibliográficos
Autores principales: Brown, Edward, Carlin, Leo M, Nerlov, Claus, Lo Celso, Cristina, Poole, Alastair W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6211653/
https://www.ncbi.nlm.nih.gov/pubmed/30393781
http://dx.doi.org/10.26508/lsa.201800061