Mechanism of anti-remodelling action of treprostinil in human pulmonary arterial smooth muscle cells

Treprostinil is applied for pulmonary arterial hypertension (PAH) therapy. However, the mechanism by which the drug achieves its beneficial effects in PAH vessels is not fully understood. This study investigated the effects of treprostinil on PDGF-BB induced remodelling parameters in isolated human...

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Detalles Bibliográficos
Autores principales: Lambers, Christopher, Kornauth, Christoph, Oberndorfer, Felicitas, Boehm, Panja M., Tamm, Michael, Klepetko, Walter, Roth, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6211661/
https://www.ncbi.nlm.nih.gov/pubmed/30383775
http://dx.doi.org/10.1371/journal.pone.0205195

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6211661/
https://www.ncbi.nlm.nih.gov/pubmed/30383775
http://dx.doi.org/10.1371/journal.pone.0205195

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