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Mechanism of anti-remodelling action of treprostinil in human pulmonary arterial smooth muscle cells
Treprostinil is applied for pulmonary arterial hypertension (PAH) therapy. However, the mechanism by which the drug achieves its beneficial effects in PAH vessels is not fully understood. This study investigated the effects of treprostinil on PDGF-BB induced remodelling parameters in isolated human...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6211661/ https://www.ncbi.nlm.nih.gov/pubmed/30383775 http://dx.doi.org/10.1371/journal.pone.0205195 |