Simplified, automated methods for assessing pixel intensities of fluorescently-tagged drugs in cells

Assessing the cytoplasmic uptake of fluorescently-tagged drugs in heterogeneous cell types currently involves time-consuming manual segmentation of confocal microscopy images. We developed a set of methods that incorporate map algebra techniques to facilitate and expedite image segmentation, particu...

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Detalles Bibliográficos
Autores principales: Kachelmeier, Allan, Shola, Tsering, Meier, William B., Johnson, Anastasiya, Jiang, Meiyan, Steyger, Peter S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6211712/
https://www.ncbi.nlm.nih.gov/pubmed/30383813
http://dx.doi.org/10.1371/journal.pone.0206628

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6211712/
https://www.ncbi.nlm.nih.gov/pubmed/30383813
http://dx.doi.org/10.1371/journal.pone.0206628

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