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Simplified, automated methods for assessing pixel intensities of fluorescently-tagged drugs in cells
Assessing the cytoplasmic uptake of fluorescently-tagged drugs in heterogeneous cell types currently involves time-consuming manual segmentation of confocal microscopy images. We developed a set of methods that incorporate map algebra techniques to facilitate and expedite image segmentation, particu...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6211712/ https://www.ncbi.nlm.nih.gov/pubmed/30383813 http://dx.doi.org/10.1371/journal.pone.0206628 |