Tumor-promoting effects of pancreatic cancer cell exosomes on THP-1-derived macrophages

Pancreatic ductal adenocarcinoma (PDAC) tumor growth is enhanced by tumor-associated macrophages (TAMs), yet the mechanisms by which tumor cells and TAMs communicate are not fully understood. Here we show that exosomes secreted by PDAC cell lines differed in their surface proteins, lipid composition...

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Detalles Bibliográficos
Autores principales: Linton, Samuel S., Abraham, Thomas, Liao, Jason, Clawson, Gary A., Butler, Peter J., Fox, Todd, Kester, Mark, Matters, Gail L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6211741/
https://www.ncbi.nlm.nih.gov/pubmed/30383833
http://dx.doi.org/10.1371/journal.pone.0206759

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6211741/
https://www.ncbi.nlm.nih.gov/pubmed/30383833
http://dx.doi.org/10.1371/journal.pone.0206759

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