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A k-mer-based method for the identification of phenotype-associated genomic biomarkers and predicting phenotypes of sequenced bacteria

We have developed an easy-to-use and memory-efficient method called PhenotypeSeeker that (a) identifies phenotype-specific k-mers, (b) generates a k-mer-based statistical model for predicting a given phenotype and (c) predicts the phenotype from the sequencing data of a given bacterial isolate. The...

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Detalles Bibliográficos
Autores principales: Aun, Erki, Brauer, Age, Kisand, Veljo, Tenson, Tanel, Remm, Maido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6211763/
https://www.ncbi.nlm.nih.gov/pubmed/30346947
http://dx.doi.org/10.1371/journal.pcbi.1006434