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Computationally-guided drug repurposing enables the discovery of kinase targets and inhibitors as new schistosomicidal agents
The development of novel therapeutics is urgently required for diseases where existing treatments are failing due to the emergence of resistance. This is particularly pertinent for parasitic infections of the tropics and sub-tropics, referred to collectively as neglected tropical diseases, where the...
Autores principales: | Giuliani, Sandra, Silva, Arthur C., Borba, Joyce V. V. B., Ramos, Pablo I. P., Paveley, Ross A., Muratov, Eugene N., Andrade, Carolina Horta, Furnham, Nicholas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6211772/ https://www.ncbi.nlm.nih.gov/pubmed/30346968 http://dx.doi.org/10.1371/journal.pcbi.1006515 |
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