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Pannexin 1 regulates adipose stromal cell differentiation and fat accumulation

Pannexin 1 (Panx1) is a channel-forming glycoprotein important in paracrine signaling and cellular development. In this study, we discovered that mice globally lacking Panx1 (KO) have significantly greater total fat mass and reduced lean mass compared to wild type (WT) mice under a normal diet. Desp...

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Detalles Bibliográficos
Autores principales: Lee, Vanessa R., Barr, Kevin J., Kelly, John J., Johnston, Danielle, Brown, Cody F. C., Robb, Kevin P., Sayedyahossein, Samar, Huang, Kenneth, Gros, Robert, Flynn, Lauren E., Penuela, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212408/
https://www.ncbi.nlm.nih.gov/pubmed/30385873
http://dx.doi.org/10.1038/s41598-018-34234-9