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Pannexin 1 regulates adipose stromal cell differentiation and fat accumulation
Pannexin 1 (Panx1) is a channel-forming glycoprotein important in paracrine signaling and cellular development. In this study, we discovered that mice globally lacking Panx1 (KO) have significantly greater total fat mass and reduced lean mass compared to wild type (WT) mice under a normal diet. Desp...
Autores principales: | Lee, Vanessa R., Barr, Kevin J., Kelly, John J., Johnston, Danielle, Brown, Cody F. C., Robb, Kevin P., Sayedyahossein, Samar, Huang, Kenneth, Gros, Robert, Flynn, Lauren E., Penuela, Silvia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212408/ https://www.ncbi.nlm.nih.gov/pubmed/30385873 http://dx.doi.org/10.1038/s41598-018-34234-9 |
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