Cargando…

Overexpression of CD98 in intestinal epithelium dysregulates miRNAs and their targeted proteins along the ileal villus-crypt axis

CD98 has been implicated in the experimental model of inflammatory bowel disease. We have previously shown that IEC-specific overexpression of CD98 mediates intestinal inflammation and intestinal epithelial barrier dysfunction. Mice overexpressing CD98 exhibited severe colitis and a greater suscepti...

Descripción completa

Detalles Bibliográficos
Autores principales: Han, Moon K., Baker, Mark, Zhang, Yuchen, Yang, Chunhua, Zhang, Mingzhen, Garg, Pallavi, Viennois, Emilie, Merlin, Didier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212412/
https://www.ncbi.nlm.nih.gov/pubmed/30385787
http://dx.doi.org/10.1038/s41598-018-34474-9