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Epigenetic enzymes influenced by oxidative stress and hypoxia mimetic in osteoblasts are differentially expressed in patients with osteoporosis and osteoarthritis

Epigenetic mechanisms including posttranslational histone modifications and DNA methylation are emerging as important determinants of bone homeostasis. With our case-control study we aimed to identify which chromatin-modifying enzymes could be involved in the pathology of postmenopausal osteoporosis...

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Detalles Bibliográficos
Autores principales: Vrtačnik, Peter, Zupan, Janja, Mlakar, Vid, Kranjc, Tilen, Marc, Janja, Kern, Barbara, Ostanek, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212423/
https://www.ncbi.nlm.nih.gov/pubmed/30385847
http://dx.doi.org/10.1038/s41598-018-34255-4