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Epigenetic enzymes influenced by oxidative stress and hypoxia mimetic in osteoblasts are differentially expressed in patients with osteoporosis and osteoarthritis
Epigenetic mechanisms including posttranslational histone modifications and DNA methylation are emerging as important determinants of bone homeostasis. With our case-control study we aimed to identify which chromatin-modifying enzymes could be involved in the pathology of postmenopausal osteoporosis...
Autores principales: | Vrtačnik, Peter, Zupan, Janja, Mlakar, Vid, Kranjc, Tilen, Marc, Janja, Kern, Barbara, Ostanek, Barbara |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212423/ https://www.ncbi.nlm.nih.gov/pubmed/30385847 http://dx.doi.org/10.1038/s41598-018-34255-4 |
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