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Reciprocal inhibition of YAP/TAZ and NF-κB regulates osteoarthritic cartilage degradation

Osteoarthritis is one of the leading causes of pain and disability in the aged population due to articular cartilage damage. This warrants investigation of signaling mechanisms that could protect cartilage from degeneration and degradation. Here we show in a murine model of experimental osteoarthrit...

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Detalles Bibliográficos
Autores principales: Deng, Yujie, Lu, Jinqiu, Li, Wenling, Wu, Ailing, Zhang, Xu, Tong, Wenxue, Ho, Kiwai Kevin, Qin, Ling, Song, Hai, Mak, Kinglun Kingston
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212432/
https://www.ncbi.nlm.nih.gov/pubmed/30385786
http://dx.doi.org/10.1038/s41467-018-07022-2