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Direct visualization of DNA baton pass between replication factors bound to PCNA

In Eukarya and Archaea, the lagging strand synthesis is accomplished mainly by three key factors, DNA polymerase (Pol), flap endonuclease (FEN), and DNA ligase (Lig), in the DNA replication process. These three factors form important complexes with proliferating cell nuclear antigen (PCNA), thereby...

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Detalles Bibliográficos
Autores principales: Mayanagi, Kouta, Ishino, Sonoko, Shirai, Tsuyoshi, Oyama, Takuji, Kiyonari, Shinichi, Kohda, Daisuke, Morikawa, Kosuke, Ishino, Yoshizumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212441/
https://www.ncbi.nlm.nih.gov/pubmed/30385773
http://dx.doi.org/10.1038/s41598-018-34176-2