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Enoxacin and bis-enoxacin stimulate 4T1 murine breast cancer cells to release extracellular vesicles that inhibit osteoclastogenesis

Enoxacin and its bone-seeking bisphosphonate derivative, bis-enoxacin, have recently captured attention as potential therapeutic agents for the treatment of cancer and bone disease. No differences in growth or survival of 4T1 murine breast cancer cells were detected at a concentration of 50 µM of en...

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Detalles Bibliográficos
Autores principales: Vracar, Taylor C., Zuo, Jian, Park, JeongSu, Azer, Demyana, Mikhael, Christy, Holliday, Sophia A., Holsey, Dontreyl, Han, Guanghong, VonMoss, Lindsay, Neubert, John K., Rody, Wellington J., Chan, Edward K. L., Holliday, L. Shannon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212457/
https://www.ncbi.nlm.nih.gov/pubmed/30385810
http://dx.doi.org/10.1038/s41598-018-34698-9