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Integrating in vitro experiments with in silico approaches for Glioblastoma invasion: the role of cell-to-cell adhesion heterogeneity

Glioblastoma cells adopt migration strategies to invade into the brain parenchyma ranging from individual to collective mechanisms, whose role and dynamics are not yet fully understood. In this work, we explore Glioblastoma heterogeneity and recapitulate its invasive patterns both in vitro, by utili...

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Detalles Bibliográficos
Autores principales: Oraiopoulou, M.-E., Tzamali, E., Tzedakis, G., Liapis, E., Zacharakis, G., Vakis, A., Papamatheakis, J., Sakkalis, V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212459/
https://www.ncbi.nlm.nih.gov/pubmed/30385804
http://dx.doi.org/10.1038/s41598-018-34521-5