ACE-inhibition induces a cardioprotective transcriptional response in the metabolic syndrome heart

Cardiovascular disease associated with metabolic syndrome has a high prevalence, but the mechanistic basis of metabolic cardiomyopathy remains poorly understood. We characterised the cardiac transcriptome in a murine metabolic syndrome (MetS) model (LDLR−/−; ob/ob, DKO) relative to the healthy, cont...

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Detalles Bibliográficos
Autores principales: Yakubova, Aziza, Thorrez, Lieven, Svetlichnyy, Dmitry, Zwarts, Liesbeth, Vulsteke, Veerle, Laenen, Griet, Oosterlinck, Wouter, Moreau, Yves, Dehaspe, Luc, Van Houdt, Jeroen, Cortés-Calabuig, Álvaro, De Moor, Bart, Callaerts, Patrick, Herijgers, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212468/
https://www.ncbi.nlm.nih.gov/pubmed/30385846
http://dx.doi.org/10.1038/s41598-018-34547-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212468/
https://www.ncbi.nlm.nih.gov/pubmed/30385846
http://dx.doi.org/10.1038/s41598-018-34547-9

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