PINK1/Parkin-mediated mitophagy is activated in cisplatin nephrotoxicity to protect against kidney injury

Cisplatin is a widely used chemotherapeutic drug with notorious toxicity in the kidneys, which involves mitochondrial dysfunction and damage in renal tubular cells. Mitophagy is a form of selective autophagy that removes damaged or dysfunctional mitochondria to maintain cellular homeostasis. In this...

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Detalles Bibliográficos
Autores principales: Wang, Ying, Tang, Chengyuan, Cai, Juan, Chen, Guochun, Zhang, Dongshan, Zhang, Zhuohua, Dong, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212494/
https://www.ncbi.nlm.nih.gov/pubmed/30385753
http://dx.doi.org/10.1038/s41419-018-1152-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212494/
https://www.ncbi.nlm.nih.gov/pubmed/30385753
http://dx.doi.org/10.1038/s41419-018-1152-2

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