The SGK3-triggered ubiquitin–proteasome degradation of podocalyxin (PC) and ezrin in podocytes was associated with the stability of the PC/ezrin complex

Podocyte damage is commonly accompanied by destabilization of the podocalyxin (PC)/ezrin complex. Serum- and glucocorticoid-inducible kinase 3 (SGK3) plays a role in the maintenance of podocyte function, but the details of this role are poorly understood. Herein we demonstrated that SGK3 and its dow...

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Detalles Bibliográficos
Autores principales: Yuan, Ya-Pei, Zhao, Hong, Peng, Li-Qin, Li, Zi-Fang, Liu, Song, Yuan, Cheng-Yan, Mwamunyi, Mercy-Julian, Pearce, David, Yao, Li-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212497/
https://www.ncbi.nlm.nih.gov/pubmed/30385740
http://dx.doi.org/10.1038/s41419-018-1161-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212497/
https://www.ncbi.nlm.nih.gov/pubmed/30385740
http://dx.doi.org/10.1038/s41419-018-1161-1

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