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Target site specificity and in vivo complexity of the mammalian arginylome

Protein arginylation mediated by arginyltransferase ATE1 is a key regulatory process essential for mammalian embryogenesis, cell migration, and protein regulation. Despite decades of studies, very little is known about the specificity of ATE1-mediated target site recognition. Here, we used in vitro...

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Detalles Bibliográficos
Autores principales: Wang, Junling, Pejaver, Vikas Rao, Dann, Geoffrey P., Wolf, Max Y., Kellis, Manolis, Huang, Yun, Garcia, Benjamin A., Radivojac, Predrag, Kashina, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212499/
https://www.ncbi.nlm.nih.gov/pubmed/30385798
http://dx.doi.org/10.1038/s41598-018-34639-6