Triciribine increases LDLR expression and LDL uptake through stabilization of LDLR mRNA

Low-density lipoprotein receptor (LDLR) is a key regulator of the metabolism of plasma low-density lipoprotein cholesterol (LDL-C), the elevated levels of which are associated with an increased risk of cardiovascular disease. Therefore, enhancing LDLR expression represents a potent treatment strateg...

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Detalles Bibliográficos
Autores principales: Bjune, Katrine, Wierød, Lene, Naderi, Soheil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212527/
https://www.ncbi.nlm.nih.gov/pubmed/30385871
http://dx.doi.org/10.1038/s41598-018-34237-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212527/
https://www.ncbi.nlm.nih.gov/pubmed/30385871
http://dx.doi.org/10.1038/s41598-018-34237-6

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