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Enhanced pharmacological efficacy of sumatriptan due to modification of its physicochemical properties by inclusion in selected cyclodextrins

The study focused on the pharmacological action of sumatriptan, in particular its antiallodynic and antihyperalgesic properties, as an effect of cyclodextrinic inclusion of sumatriptan, resulting in changes of its physicochemical qualities such as dissolution and permeability through artificial biol...

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Detalles Bibliográficos
Autores principales: Paczkowska, Magdalena, Mizera, Mikołaj, Sałat, Kinga, Furgała, Anna, Popik, Piotr, Knapik-Kowalczuk, Justyna, Krause, Anna, Szymanowska-Powałowska, Daria, Fojud, Zbigniew, Kozak, Maciej, Paluch, Marian, Cielecka-Piontek, Judyta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212534/
https://www.ncbi.nlm.nih.gov/pubmed/30385844
http://dx.doi.org/10.1038/s41598-018-34554-w