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Enhanced pharmacological efficacy of sumatriptan due to modification of its physicochemical properties by inclusion in selected cyclodextrins
The study focused on the pharmacological action of sumatriptan, in particular its antiallodynic and antihyperalgesic properties, as an effect of cyclodextrinic inclusion of sumatriptan, resulting in changes of its physicochemical qualities such as dissolution and permeability through artificial biol...
Autores principales: | Paczkowska, Magdalena, Mizera, Mikołaj, Sałat, Kinga, Furgała, Anna, Popik, Piotr, Knapik-Kowalczuk, Justyna, Krause, Anna, Szymanowska-Powałowska, Daria, Fojud, Zbigniew, Kozak, Maciej, Paluch, Marian, Cielecka-Piontek, Judyta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212534/ https://www.ncbi.nlm.nih.gov/pubmed/30385844 http://dx.doi.org/10.1038/s41598-018-34554-w |
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