Observations on spontaneous tumor formation in mice overexpressing mitotic kinesin Kif14

The KIF14 locus is gained and overexpressed in various malignancies, with prognostic relevance. Its protein product, a mitotic kinesin, accelerates growth of normal mammary epithelial cells in vitro and retinoblastoma tumours in a mouse model, while KIF14 knockdown blocks growth of brain, liver, ova...

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Detalles Bibliográficos
Autores principales: Sishtla, Kamakshi, Pitt, Natalie, Shadmand, Mehdi, O’Hare, Michael N., Sulaiman, Rania S., Sinn, Anthony L., Condon, Keith, Pollok, Karen E., Sandusky, George E., Corson, Timothy W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212535/
https://www.ncbi.nlm.nih.gov/pubmed/30385851
http://dx.doi.org/10.1038/s41598-018-34603-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212535/
https://www.ncbi.nlm.nih.gov/pubmed/30385851
http://dx.doi.org/10.1038/s41598-018-34603-4

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