Mutation Status and Immunohistochemical Correlation of KRAS, NRAS, and BRAF in 260 Chinese Colorectal and Gastric Cancers

KRAS, NRAS and BRAF are kinases involved in the RAS-RAF-MAPK signaling pathway and also potential tumor-driven genes. Patients with KRAS/NRAS/BRAF mutations are resistant to anti-EGFR monoclonal antibody therapy. The main purpose of this study is to investigate the mutation status and distribution o...

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Detalles Bibliográficos
Autores principales: Yang, Qiwei, Huo, Sibo, Sui, Yujie, Du, Zhenwu, Zhao, Haiyue, Liu, Yu, Li, Wei, Wan, Xin, Liu, Tongjun, Zhang, Guizhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212577/
https://www.ncbi.nlm.nih.gov/pubmed/30416987
http://dx.doi.org/10.3389/fonc.2018.00487

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212577/
https://www.ncbi.nlm.nih.gov/pubmed/30416987
http://dx.doi.org/10.3389/fonc.2018.00487

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