Cargando…

Both Ser361 phosphorylation and the C‐arrestin domain of thioredoxin interacting protein are important for cell cycle blockade at the G1/S checkpoint

Thioredoxin interacting protein (TXNIP) is a novel tumor suppressor that is down‐regulated in several cancer tissues and tumor cell lines. Overexpression of TXNIP causes cell cycle arrest at the G1/S checkpoint in the hepatocellular carcinoma cell line HuH‐7. TXNIP contains putative phosphorylation...

Descripción completa

Detalles Bibliográficos
Autores principales: Kamitori, Kazuyo, Yamaguchi, Fuminori, Dong, Youyi, Hossain, Akram, Katagi, Ayako, Noguchi, Chisato, Hirata, Yuko, Tsukamoto, Ikuko, Hatano, Naoya, Tokuda, Masaaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212649/
https://www.ncbi.nlm.nih.gov/pubmed/30410860
http://dx.doi.org/10.1002/2211-5463.12518