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Both Ser361 phosphorylation and the C‐arrestin domain of thioredoxin interacting protein are important for cell cycle blockade at the G1/S checkpoint
Thioredoxin interacting protein (TXNIP) is a novel tumor suppressor that is down‐regulated in several cancer tissues and tumor cell lines. Overexpression of TXNIP causes cell cycle arrest at the G1/S checkpoint in the hepatocellular carcinoma cell line HuH‐7. TXNIP contains putative phosphorylation...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212649/ https://www.ncbi.nlm.nih.gov/pubmed/30410860 http://dx.doi.org/10.1002/2211-5463.12518 |