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RbpA relaxes promoter selectivity of M. tuberculosis RNA polymerase

The transcriptional activator RbpA associates with Mycobacterium tuberculosis RNA polymerase (MtbRNAP) during transcription initiation, and stimulates formation of the MtbRNAP-promoter open complex (RPo). Here, we explored the influence of promoter motifs on RbpA-mediated activation of MtbRNAP conta...

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Detalles Bibliográficos
Autores principales: Sudalaiyadum Perumal, Ayyappasamy, Vishwakarma, Rishi Kishore, Hu, Yangbo, Morichaud, Zakia, Brodolin, Konstantin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212719/
https://www.ncbi.nlm.nih.gov/pubmed/30102406
http://dx.doi.org/10.1093/nar/gky714