Structural analysis of the ternary complex between lamin A/C, BAF and emerin identifies an interface disrupted in autosomal recessive progeroid diseases

Lamins are the main components of the nucleoskeleton. Whereas their 3D organization was recently described using cryoelectron tomography, no structural data highlights how they interact with their partners at the interface between the inner nuclear envelope and chromatin. A large number of mutations...

Descripción completa

Detalles Bibliográficos
Autores principales: Samson, Camille, Petitalot, Ambre, Celli, Florian, Herrada, Isaline, Ropars, Virginie, Le Du, Marie-Hélène, Nhiri, Naïma, Jacquet, Eric, Arteni, Ana-Andrea, Buendia, Brigitte, Zinn-Justin, Sophie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212729/
https://www.ncbi.nlm.nih.gov/pubmed/30137533
http://dx.doi.org/10.1093/nar/gky736

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212729/
https://www.ncbi.nlm.nih.gov/pubmed/30137533
http://dx.doi.org/10.1093/nar/gky736

Ejemplares similares